Search results for "Protamine zinc insulin"

Altered desaturase activities and fatty acid composition in liver microsomes of spontaneously diabetic Wistar BB rat.

1992

We examined the activities of delta 9, delta 6 and delta 5 desaturases and fatty acid composition of liver microsomes in the insulin-dependent spontaneously diabetic adult female Wistar Bio-Breeding (BB) rat. The diabetic BB rats were subcutaneously injected with different doses of protamine zinc insulin in order to be killed in hyper-, normo- or hypo-glycemic states. Desaturase activities, which are partially inhibited by spontaneous diabetes during the normo- and hyper-glycemic periods, were similarly affected by the various insulin treatment; delta 9 desaturase activity being more depressed than the desaturase activities of either delta 6 of delta 5. Insulin treatment with 10 I.U./kg bod…